大型三甲医院临床数据中心系统的建设与应用

摘要

Objective: The Construction of Clinical Data Repository is based on integration platform, it integrated all the patient treatment information and formed a patient-centered clinical data center. Method: Applying HL7v3 and CDA standards, the structure and semantics of clinical documents are redefined standardly and locally. The communication and data exchange between heterogeneous systems are achieved with 41 clinical criteria documents. The F5 is used to equalization access security and the Golden Gate technical is used to support storage security. Results: Successfully implemented the full life cycle management of patient information, CDR reached 5.47 million patient records, 410 million clinical, 1.5TB of data, while providing a flexible user rights management and various forms of access systems, greatly improving the ease of system use. Conclusion: CDR achieved the interacts among multiple clinical information systems and various clinical documents, accumulated a lot of valuable data for subsequent clinical medicine, teaching, research, management, lay a solid foundation for the use of large data analysis on CDR data mining use, and promote innovation and development of new models of medical research.%目的：利用医院业务集成平台，整合患者在院诊疗期间所有诊疗信息，形成以患者为中心的临床数据中心（Clinical Data Repository，CDR）。方法：应用HL7v3和CDA标准，对临床文档的结构和语义进行标准化和本地化定义，实现41类临床标准文档的结构化存储、异构系统间的通信和数据交换。利用F5负载均衡技术和Golden Gate技术保障系统的访问安全和存储安全。结果：成功实现了对患者信息的全生命周期管理，CDR采集了547万个患者记录，4.1亿条临床数据，数据容量达1.5TB。CDR提供了灵活的用户权限管理和多种系统访问形式，提高了系统使用的便利性。结论：CDR系统的建设实现多个临床信息系统的交互与临床文档共享，积累大量临床数据，为后续的临床、教育和研究奠定了坚实基础。