A CONVENIENT APPROACH OF DIYNE ALCOHOL AND TRIYNE ALCOHOL BY COPPER (I) AND PHASE TRANSFER CONDITION CATALYZED PROPARGYLATION OF PROPARGYL ALCOHOL

摘要

The copper(Ⅰ) catalyzed coupling reaction of substituted propargyl tosylate with propargyl alcohol proceeds smoothly at room temperature to give 2,5-diynyl alcohol under solid-liquid phase transfer condition. A number of 2,5-diynyl alcohols and 2,5,8-triynyl alcohols were synthesized in this way in good yield.