Electrospun PVA Nanofibrous Membranes Reinforced with Silver Nanoparticles Impregnated Cellulosic Fibers:Morphology and Antibacterial Property

摘要

To enhance the mechanical and antibacterial properties of silver nanoparticle impregnated cellulosic fibers,carboxy-cellulose nanocrystals(CCNs)were grafted with chitooligosaccharide(COS),which was used as a stabilizer for silver nanoparticles(AgNPs).Nanofibrous membranes reinforced with silver nanoparticle impregnated cellulosic fibers(CCN-COS-AgNP)were prepared via electrospinning using polyvinyl alcohol(PVA)as a matrix.The effects of CCN-COS-AgNP contents on the morphology,surface composition,mechanical properties,and antibacterial performances of the prepared CCN-COS-AgNP/PVA membranes were examined.The addition of CCN-COS-AgNP certainly improved the mechanical properties and antibacterial performances of the PVA nanofibers.The tensile strength was significantly increased from 4.40 MPa to 8.60 MPa when 8%CCN-COS-AgNP(mass ratio)was introduced.When 10%(mass ratio)CCN-COS-AgNP was added,the nanofibers showed an excellent antibacterial activity for S.aureus(Staphylococcus aureus)and E.coli(Escherichia coli),with the maximum inhibition zones of 2.30 and 1.60 cm,respectively.Moreover,the 2%(mass ratio)CCN-COS-AgNP/PVA fibrous membrane showed 126%cell viability for mg63 human osteoblasts.The electrospun PVA membrane has great potential application in biomedical field.