微球形4-氨基吡啶分子模板聚合物的合成及结合性质研究

摘要

利用分子印迹技术, 通过沉淀聚合方法合成了对4-氨基吡啶具有选择性结合能力的微球形分子模板聚合物. 通过静态结合方法研究了该聚合物的选择性结合能力以及不同溶剂及引发剂的用量对聚合物形态及球状聚合物粒径大小的影响. 底物选择性实验结果表明, 与结构相似的化合物相比, 4-氨基吡啶球形分子模板聚合物对4-氨基吡啶显示出强的选择性.%The molecularly imprinted microspheres using 4-aminopyridine as template were prepared with precipitation polymerization. The batch way was used to investigate the selectively binding ability of the microspheres for 4-aminopyridine. The effects of different amount of solvent and initiator on the shape and the size of the particles were studied. The substrate selectivity of the polymer was investigated. The results showed that the imprinted polymer exhibited a high affinity for 4-aminopyridine among the tested compounds.