首页> 中文期刊> 《细胞研究:英文版》 >NIH 3T3 cells malignantly transformed by mot-2 showinactivation and cytoplasmic sequestration of the p53protein

NIH 3T3 cells malignantly transformed by mot-2 showinactivation and cytoplasmic sequestration of the p53protein

         

摘要

INTRODUCTIONInvolvementandinactivationofp53,atumorsuppressorandcellulartranscriptionfactorincellularimmortalizationhasbeenwelldocumented[1-4].Variousactivitiesofp53proteininvolveitsfunctionaldomains,viz.,anamino--terminustransactivationdomain(aminoac...

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