Commentary on: Mobley AJ, Lam YW, Lau KM, Pais VM, Lesperance JO, Steadman B, et al. Monitoring the serological Proteome Colon, thelatest modality in prostate cancer detection. J Urol 2004; 172: 331-7.

摘要

This manuscript examines the utility, utilizing the Ciphergen Protein Biosystem II, to develop a fingerprint for the diagnosis of prostate cancer. The investigators compared samples from control individuals as well as those with prostate cancer. In doing so, they utilize several chip platforms on which to examine the resulting protein peaks. In summary, these studies find a peak pattern that is able to distinguish the individuals with prostate cancer from those without the disease.