Aim To investigate the clinical presentation, diagnosis of cancer associated with sarcoidosis, and the relationship between them. Methods In this article , we described a case of gastric cancer associated with systemic sarcoidosis , and the correlated literatures were reviewed. Results Sarcoidosis had no specific clinical presentation ,was hard to diagnose and had a high misdiagnosis rate. Clinicians needed novel non invasive diagnostic methods to differentiate cancer from benign sarcoid reactions. The 18-Fuorodeoxyglucose ( 18FDG) PET-CT-scan failed in this indication . but the adjunctiol of a[ 3-( 18 ) F ] -alpha-methyltyrosine ( ( 18 ) F-FMT) PET-scan could be useful. Biopsies was still necessary in most of the cases. Relationships between Sarcoidosis and cancer had been suspected for a long time. Nevertheless, few evidence had been reported until recently , and further study was needed. Conclusion This article suggest that the possibility of systemic sarcoidosis should be considered in cases with established cancer and newly disclosed radiographic findings.%目的 探讨恶性肿瘤合并结节病的临床表现、诊断及两者之间的关系.方法 报道1例胃癌合并结节病病例,并复习有关文献.结果 结节病表现无特异性,诊断困难,误诊率高,非侵袭性的检查方法包括18F-FDG-PET-CT难以区分结节病、恶性肿瘤及癌伴引流区淋巴结结节病样肉芽肿反应(SGR),活检仍是必须的,而18F-FMT-PET(18F标记甲基酪氨酸-PET)有助于结节病与恶性肿瘤的鉴别.恶性肿瘤合并结节病国内尚无报道,两者之间是否存在某种关联,尚需进一步研究.结论 该病例说明对明确诊断为恶性肿瘤的患者,影像学提示淋巴结肿大,需考虑有合并结节病可能.
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