Objective To study the efficacy of intensified antihypertensive, sedative intervention on the micro-pump infusion of propofol and sodium nitroprusside on the patients in acute stage of cerebral hemorrhage. Methods Seventy-eight cases of hypertensive cerebral hemorrhage were randomly divided into two groups, the patients of study group were treated with propofol combined with sodium nitroprusside, via micro-pump; control group as a step-down group. Data of changes of hematoma, neurological function score and the motality rate of cerebral infarction were collected. Results The size of the hematoma, neurological function score of the patients between the two groups had a significant difference; while the mortality within 1 month, the incidence of cerebral infarction had no difference. Conclusion Treatment of patients with cerebral hemorrhage in acute stage with controlled depressurization using propofol combined with sodium nitroprusside via micropump, would be helpful for reducing elevated blood pressure, reduce the complications caused by elevated blood pressure, deter the enlargement of hematoma and the patients might get favorable outcomes.%目的 研究微泵输注丙泊酚和硝普钠在脑出血急性期的控制性强化降压、镇静干预对患者病情及预后的影响.方法 对78例高血压脑出血患者随机分为两组,研究组为丙泊酚复合硝普钠组,采取微泵输入控制性降压;对照组为非降压组.比较血肿变化、神经功能评分及病死率、脑梗死发生率等指标.结果 两组患者在血肿大小、神经功能评分差异有显著性;1个月后的病死率、脑梗死的发生率无差异.结论 在动脉硬化性脑出血患者出血急性期使用丙泊酚复合硝普钠控制性降压,将有利于降低血压升高引起的并发症、减少血肿增大几率,有利于患者预后.
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