生物及金属可降解支架在冠状动脉粥样硬化性心脏病介入治疗中的研究进展

摘要

Percutaneous coronary intervention has been key to the development of the drug-eluting stent, and has allowed for the rate of in-stent restenosis to drop below 10%. Biodegradable and bioabsorbable stents aim to provide temporary mechanical support to the vessel wall and subsequently dissolve. After which, vascular integrity and function are restored. This article examines progress made on biodegradable scaffolds and metal bioabsorbable stents.%冠状动脉粥样硬化性心脏病介入治疗已发展至药物洗脱支架时代,使血管再狭窄率降至10%以下,由于金属支架在体内长期留存可能会引发晚期不良反应.生物及金属可降解支架在置入早期对血管壁起到支撑作用,之后逐渐降解至消失,使血管的完整性和功能得以恢复,此类支架是未来支架的发展方向.现将重点阐述生物可降解支架及金属可吸收支架的研究进展.