植物MPK信号通路与信号分子H2O2和NO之间的相互关系

摘要

The mitogen-activated protein kinase (MPK) cascades are well known as highly conserved signaling transduction pathways found in all eukaryotes,which regulate numerous processes in plants,including biotic and abiotic stress responses and developmental programs. Hydrogen peroxide (H2O2) and nitric oxide (NO) acting as important signaling molecules also mediate a wide array of responses to developmental cues and environmental stresses in plants. Recently,many studies have revealed a much more complex relationship between MPK cascades and signaling molecular H2O2 or NO. On the one hand, MPK signaling pathways are not only induced by H2O2 or NO but can also regulate the production or scavenging of H2O2 or NO in some signal transduction pathways of many stimulating factors,on the other hand,MPK cascades and H2O2 or NO signaling are functional respectively in different signal pathways stimulated by a same factor. In this paper,the recent progress on the interrelationship between MPK cascades and H2O2 or NO signaling is reviewed and discussed. Finally,the problems remained in this field are analyzed.%促分裂原活化蛋白激酶(MPK)级联途径是真核细胞中普遍存在且保守的信号传导通路,广泛参与植物生长发育和植物抵抗生物和非生物胁迫的防御反应.过氧化氢(H2O2)和一氧化氮(NO)作为重要的信使分子也广泛参与植物生长发育和防御反应的信号传导.近年来,研究也表明MPK信号通路与信号分子H2O2和NO之间存在着多种复杂的关系.一方面,在一些刺激的信号传递过程中,MPK信号通路参与了信号分子H2O2和NO的产生、清除或其信号的向下传递等过程；另一方面,在有些刺激的信号传递过程中,它们位于不同的信号传递途经中,行使不同的功能.本文就目前植物MPK信号通路与H2O2和NO之间相互关系的研究现状进行了综述和分析,并指出了该研究领域存在的问题.