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The Immune Checkpoint B7x Promotes the Induction of Regulatory T Cells in the Tumor Microenvironment and Mediates Resistance to Immunotherapy

机译：免疫检查点B7X促进肿瘤微环境中调节性T细胞的诱导，并介导对免疫疗法的抗性

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作者
John, Peter.;
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作者单位

Albert Einstein College of Medicine.;

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授予单位 Albert Einstein College of Medicine.;
学科
学位 Ph.D.
年度 2022
页码 244 p.
总页数 244
原文格式 PDF
正文语种 eng
中图分类 AAI28150085;
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专利

1. Checkpoint regulator B7x is epigenetically regulated by HDAC3 and mediates resistance to HDAC inhibitors by reprogramming the tumor immune environment in colorectal cancer [J] . Yuxin Li, Yao Liu, Na Zhao, Cell death & disease. . 2020,第9期

机译：检查点调节剂B7X通过HDAC3进行齿膜监管，并通过在结直肠癌中重编程肿瘤免疫环境来介导对HDAC抑制剂的抗性
2. Targeting Endoglin-Expressing Regulatory T Cells in the Tumor Microenvironment Enhances the Effect of PD1 Checkpoint Inhibitor Immunotherapy [J] . Schoonderwoerd Mark J. A., Koops Maaike F. M., Angela Ricardo A., Clinical cancer research: an official journal of the American Association for Cancer Research . 2020,第14期

机译：靶向肿瘤微环境中表达内皮林的调节性T细胞增强了PD1检查点抑制剂免疫疗法的影响
3. Tumor microenvironment dictates regulatory T cell phenotype: Upregulated immune checkpoints reinforce suppressive function [J] . Hye Ryun Kim, Hyo Jin Park, Jimin Son, Journal for ImmunoTherapy of Cancer . 2019,第1期

机译：肿瘤微环境决定调节性T细胞表型：上调免疫检查点可增强抑制功能
4. The Biologic Scaffold Immune Microenvironment Inhibits Tumor Formation and Synergizes with Immunotherapy [C] . Matthew T. Wolf, Sudipto Ganguly, Radhika Narain, Society for Biomaterials annual meeting and exposition . 2019

机译：生物支架免疫微环境抑制肿瘤形成并与免疫疗法协同作用。
5. Interactions between host immune cells and tumor cells within endogenous and cytokine modulated tumor microenvironments. [D] . Moran, James Patrick. 2002

机译：内源性和细胞因子调节的肿瘤微环境中宿主免疫细胞与肿瘤细胞之间的相互作用。
6. Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells [O] . Kim C. Ohaegbulam, Weifeng Liu, Hyungjun Jeon, 2017

机译：肿瘤表达的免疫检查点B7x促进癌症进展抗原特异性CD8 T细胞衰竭和先天性免疫细胞抑制
7. Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells [O] . Kim C. Ohaegbulam, Weifeng Liu, Hyungjun Jeon, 2017

机译：表达肿瘤的免疫检查点B7X促进癌症进展和抗原特异性CD8 T细胞耗尽和抑制先天免疫细胞
8. Comparative Immunotoxicity of 2,2'-Dichlorodiethyl Sulfide and Cyclophosphamide:Evaluation of L1210 Tumor Cell Resistance, Cell-Mediated Immunity, and Humoral Immunity [R] . Blank, J. A., Joiner, R. L., Houchens, D. P., 1991

机译：2,2'-二氯二乙基硫醚和环磷酰胺的比较免疫毒性：评估L1210肿瘤细胞抗性，细胞介导的免疫和体液免疫

The Immune Checkpoint B7x Promotes the Induction of Regulatory T Cells in the Tumor Microenvironment and Mediates Resistance to Immunotherapy

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