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Effect of colostral administration practices on serum immunoglobulin concentration in dairy calves.

机译:腹腔给药对乳牛犊血清免疫球蛋白浓度的影响。

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摘要

Despite the accumulated understanding of the factors which affect passive transfer of colostral immunoglobulins and its recognized importance in dairy calves, approximately 35-40% of US dairy calves have inadequate passive transfer of colostral immunoglobulins. The objectives of this research were (1) determine the frequency and role of precolostral serum immunoglobulin concentration in dairy calves, (2) Compare various methods in assessing colostral immunoglobulin concentration, (3) determine the amount of colostral IgG required for adequate passive transfer of colostral immunoglobulins in calves fed colostrum by oroesophageal tubing and evaluate other accepted factors on passive transfer of colostral immunoglobulins in dairy bull calves, and (4) determine factors affecting serum IgG concentrations in bottle fed heifer calves.;There was no apparent link between precolostral serum immunoglobulin against common infectious agents known to be transmitted transplacentally. The weight of first milking colostrum as a test method has low sensitivity, thus its use in identifying colostrum with low IgG concentration is not justified. At least 150 to 200 g of colostral IgG is required for adequate passive transfer of colostral immunoglobulins in tube fed calves. Probability of FPT in calves ingesting 3 L at first feeding and 3 L at 12 hours was 0.05 even at low colostral IgG concentrations bottle fed calves.
机译:尽管人们对影响初次免疫的球体免疫球蛋白的转移因子的认识及其公认的重要性,但美国大约35-40%的初乳牛的初次免疫球蛋白免疫球蛋白的被动转移不足。这项研究的目的是(1)确定牛犊中初乳前血清免疫球蛋白浓度的频率和作用,(2)比较评估初乳中免疫球蛋白浓度的各种方法,(3)确定适当的被动转移肝素所需的初乳IgG量牛经口食管饲喂初乳的犊牛体内的初乳免疫球蛋白,并评估了奶牛犊牛初次被动转运体免疫球蛋白的其他公认因素,以及(4)确定影响奶牛犊牛犊牛血清IgG浓度的因素。免疫球蛋白针对已知通过胎盘传播的常见传染原。作为测试方法的初乳初乳的重量灵敏度较低,因此无法用于鉴定低IgG浓度的初乳。至少150至200 g的初乳IgG足以在试管饲牛犊中充分被动转移初乳的免疫球蛋白。首次饲喂3 L的犊牛和在12小时摄取3 L的犊牛中FPT的概率即使在初乳IgG浓度低的情况下也小于0.05。

著录项

  • 作者

    Chigerwe, Munashe.;

  • 作者单位

    University of Missouri - Columbia.;

  • 授予单位 University of Missouri - Columbia.;
  • 学科 Health Sciences Epidemiology.;Health Sciences Immunology.;Biology Veterinary Science.
  • 学位 Ph.D.
  • 年度 2008
  • 页码 127 p.
  • 总页数 127
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 动物学;预防医学、卫生学;
  • 关键词

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