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Instability of an epigenetic mark: T-bet and STAT4 influence the symmetry and plasticity of DNA methylation at the Ifng promoter in effector and memory Th2 lymphocytes

机译：表观遗传标记的不稳定性：T-bet和STAT4影响效应子和记忆Th2淋巴细胞Ifng启动子处DNA甲基化的对称性和可塑性

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作者
Williams, Christopher L.;
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作者单位

Vanderbilt University;

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授予单位 Vanderbilt University;
学科
学位 Ph.D.
年度 2013
页码 184 p.
总页数 184
原文格式 PDF
正文语种 eng
中图分类
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专利

1. STAT4 and T-bet Are Required for the Plasticity of IFN-γ Expression across Th2 Ontogeny and Influence Changes in Ifng Promoter DNA Methylation [J] . Christopher L. Williams, Marcia M. Schilling, Sung Hoon Cho, The journal of immunology . 2013,第2期

机译：STAT4和T-BET是针对OFN-γ表达的可塑性所必需的，并且IFNG启动子DNA甲基化的影响变化
2. STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation [J] . WilliamsC.L., SchillingM.M., ChoS.H., The Journal of Immunology: Official Journal of the American Association of Immunologists . 2013,第2期

机译：STAT4和T-bet是整个Th2个体中IFN-γ表达可塑性和影响Ifng启动子DNA甲基化变化所必需的
3. CD44 Reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis. [J] . Guan H, Nagarkatti PS, Nagarkatti M The Journal of Immunology: Official Journal of the American Association of Immunologists . 2011,第12期

机译：CD44通过涉及细胞因子基因启动子的DNA甲基化的表观遗传调控，相互调节脑致病性Th1 / Th17和Th2 /调节性T细胞的分化，从而控制实验性自身免疫性脑脊髓炎的发展。
4. Transcriptional Landscapes in Lymphocyte Development and Differentiation: TCF-1 Enforces Epigenetic Identity in Developing T Cells and T-BET Resolves Functionally Distinct Memory B Cells [D] . ?Johnson, John L. 2020

机译：淋巴细胞发育和分化中的转录景观：TCF-1在开发T细胞中实施表观遗传鉴定和T-BET解决功能上明显的内存B细胞
5. STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation [O] . Christopher L. Williams, Marcia M. Schilling, Sung Hoon Cho, -1

机译：STAT4和T-bet是整个Th2个体中IFN-γ表达的可塑性并影响Ifng启动子DNA甲基化变化所必需的
6. STAT4 and T-bet Are Required for the Plasticity of IFN-γ Expression across Th2 Ontogeny and Influence Changes in Ifng Promoter DNA Methylation [O] . Christopher L. Williams, Marcia M. Schilling, Sung Hoon Cho, 2013

机译：STAT4和T-BET是针对OFN-γ表达的可塑性所必需的，并且IFNG启动子DNA甲基化的影响变化

Instability of an epigenetic mark: T-bet and STAT4 influence the symmetry and plasticity of DNA methylation at the Ifng promoter in effector and memory Th2 lymphocytes

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