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Part I. Unified pharmacophore protein models of the benzodiazepine receptor subtypes. Part II. Subtype selective ligands for α5 Gaba(A) /BZ receptors

机译：第一部分。苯并二氮杂receptor受体亚型的统一药效团蛋白模型。第二部分亚型α5Gaba（A）/ BZ受体的选择性配体

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作者
Clayton, Terrill S.;
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作者单位

The University of Wisconsin - Milwaukee;

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授予单位 The University of Wisconsin - Milwaukee;
学科
学位 Ph.D.
年度 2011
页码 776 p.
总页数 776
原文格式 PDF
正文语种 eng
中图分类
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专利

1. New evidence that the pharmacological effects of benzodiazepine receptor ligands can be associated with activities at different BZ (omega) receptor subtypes. [J] . Griebel G, Perrault G, Letang V, Psychopharmacology . 1999,第2期

机译：新证据表明苯二氮卓类受体配体的药理作用可能与不同BZ（Ω）受体亚型的活性有关。
2. Pharmacophore/receptor models for GABA(A)/BzR alpha2beta3gamma2, alpha3beta3gamma2 and alpha4beta3gamma2 recombinant subtypes. Included volume analysis and comparison to alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2 subtypes. [J] . He X, Huang Q, Ma C, Drug design and discovery . 2000,第2期

机译：GABA（A）/ BzR alpha2beta3gamma2，alpha3beta3gamma2和alpha4beta3gamma2重组亚型的药理学/受体模型。包括体积分析和与alpha1beta3gamma2，alpha5beta3gamma2和alpha6beta3gamma2亚型的比较。
3. Pharmacophore/receptor models for GABA(A)/BzR alpha2beta3gamma2, alpha3beta3gamma2 and alpha4beta3gamma2 recombinant subtypes. Included volume analysis and comparison to alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2 subtypes. [J] . He X, Huang Q, Ma C, Drug design and discovery . 2000,第2期

机译：GABA（A）/ BzR alpha2beta3gamma2，alpha3beta3gamma2和alpha4beta3gamma2重组亚型的药理学/受体模型。包括体积分析和与alpha1beta3gamma2，alpha5beta3gamma2和alpha6beta3gamma2亚型的比较。
4. Application of bioinformatics algorithms to define the most important protein features contribute to GABA receptors diversity GABA receptors' diversity, bioinformatic applications [C] . Ebrahimi Mansour, Ebrahimie Esmaeil 2nd International Conference on Chemical, Biological and Environmental Engineering . 2010

机译：应用生物信息学算法定义最重要的蛋白质特征有助于GABA受体多样性GABA受体的多样性，生物信息学应用
5. I. The structure activity relationships and cytotoxic activity of analogs of tryprostatin A and B. Preparation of irreversible inhibitors for studies of mechanism of action. II. Pharmacophore/receptor models for the GABA(A)/Bz receptor subtypes. [D] . Zhang, Chunchun. 2004

机译：I.Tryprostatin A和B的类似物的结构活性关系和细胞毒性活性。不可逆抑制剂的制备，用于研究作用机理。二。 GABA（A）/ Bz受体亚型的药理学/受体模型。
6. HZ166 a Novel GABAA Receptor Subtype-Selective Benzodiazepine Site Ligand Is Antihyperalgesic in Mouse Models of Inflammatory and Neuropathic Pain [O] . Alessandra Di Lio, Dietmar Benke, Marie Besson, -1

机译：HZ166是一种新型GABAA受体亚型选择性苯并二氮卓毒性配体是炎症和神经病疼痛的小鼠模型中的抗震术
7. HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain [O] . Di Lio, Alessandra, Benke, Dietmar, Besson, Marie, 2011

机译：HZ166是一种新型的GABAA受体亚型选择性苯二氮卓类位点配体，在炎症性和神经性疼痛的小鼠模型中具有镇痛作用

Part I. Unified pharmacophore protein models of the benzodiazepine receptor subtypes. Part II. Subtype selective ligands for α5 Gaba(A) /BZ receptors

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