The synthesis and noncovalent electron-transfer studies for anthracene and dimethylaniline substituted nucleic acid bases and G-quartet formation in the absence of templating metal ions.

摘要

Electron-transfer research is one of the most active areas in chemistry and biology. This is because long-range electron-transfer plays a central role in photosynthesis and respiration as well as in "artificial photosynthesis." As a result, this process has been examined in detail experimentally and theoretically. Hydrogen-bonding networks are believed to be one of the active components of the medium the electrons traverse through. As a result, electron-transfer model systems that are formed via hydrogen-bonding interactions have drawn considerable attention. In the present work a number of anthracene and dimethylaniline substituted nucleic acid bases have been synthesized to study the electron-transfer across a Watson-Crick base pair. Results from the photophysical characterizations of these new systems are presented in this work. During the course of electron-transfer research, an unprecedented G-quartet-like crystal structure of a new guanosine derivative was obtained in the absence of a templating metal ion. The self-assembly of this new guanosine derivative was fully characterized.