Acute effects of a single bout of resistance exercise on insulin sensitivity in persons with Type-1 diabetes mellitus.

摘要

The purpose of this study was to assess the acute effects of a single bout of resistance exercise on insulin sensitivity in persons with Type-1 diabetes mellitus. Fourteen subjects participated in the study.; The general research design was a repeated measures design. The independent variables were group (between subjects factor) and time (within subjects factor). The group factor consisted of two levels: exercise and control group. The time factor consisted of three levels: pre-exercise and 12 and 36 hr post-exercise. The dependent variable was glucose infusion rate as assessed by the euglycemic-hyperinsulinemic clamp technique. Data analyses utilized a 2 x 3 repeated measures analysis of variances, one-way analysis of variances, and Student's t-tests statistics.; No significant differences existed between the exercise and control groups in anthropometric characteristics, metabolic control, duration of disease, and physical activity status. Glucose infusion rates were not significantly different between the exercise and control groups (p = .92). In addition, there were no significant differences in the glucose infusion rates across time (p = .67).; Within the limitations of the research protocol used in this study, a single bout of resistance exercise is not sufficient to induce changes in insulin sensitivity at 12 or 36 hr post-exercise in physically active people with Type-1 diabetes mellitus. The extent that this type of exercise is capable of improving insulin sensitivity persons who are less physically active or when completed at a higher exercise volume is not known and warrants further investigation.