Evaluation of accelerated test parameters for migration testing of food packaging.

摘要

This thesis focused on determining or evaluating accelerated analytical protocol for detecting potential migrants from food contact surface of conventional ink printed and/or UV/EB cured food packaging to food. Due to "offset transfer" effect of food packaging system, the need of fast and precise migration testing protocols emerged, which are in compliance with FDA recommendation and FDA guideline.;In this study, variations of migration levels by change of testing parameters such as agitation, temperature, time, simulated solvent, and solvent volume/surface area ratio were investigated. Furthermore, the comparison studies of migration level between water soluble and insoluble compounds were performed. Single-side cell extraction and gas chromatography-mass spectrometry (GC-MS) were used to detect migrant compounds.;Through the conclusion, 24-hour accelerated migration testing protocols are suggested and evaluated, which are regarded to be equivalent to the FDA recommended testing protocols.