Maturation of Cervical Vertebrae in Patients with Complete Unilateral Cleft Lip and Palate.

摘要

This retrospective cohort study of 336 lateral cephalometric radiographs from 62 children (34 males and 28 females) with non-syndromic complete unilateral cleft lip and palate from the Hospital for Sick Children and 50 non-cleft children (25 females and 25 males) from the Burlington Growth Centre. Cervical vertebral maturation stages at age 10, 12 and 14 were determined. The cervical vertebral maturation (CVM) was established using the 6-stage method described by Baccetti and coworkers. The reproducibility of classifying CVM stages was high, with an inter-rater reliability (ICC) with the standard (Baccetti et al, 2005) of 80% and intra-rater reliability of 85%. The Cervical vertebral maturation stage for both males and females with UCLP was significantly later than children without a cleft at age 10, 12 and 14. The results suggest that patients with UCLP show delayed skeletal maturation in comparison to non-cleft patients.