Applying the Apriori and FP-Growth Association Algorithms to Liver Cancer Data.

摘要

Cancer is the leading cause of deaths globally. Although liver cancer ranks only fourth in incidence worldwide among all types of cancer, its survivability rate is the lowest. Liver cancer is often diagnosed at an advanced stage, because in the early stages of the disease patients usually do not have signs or symptoms. After initial diagnosis, therapeutic options are limited and tend to be effective only for small size tumors with limited spread and minimal vascular invasion. As a result, long-term patient survival remains minimal, and has not improved in the past three decades. In order to reduce morbidity and mortality from liver cancer, improvement in early diagnosis and the evaluation of current treatments are essential.;This study tested the applicability of the Apriori and FP-Growth association data mining algorithms to liver cancer patient data, obtained from the British Columbia Cancer Agency. The data was used to develop association rules which indicate what combinations of factors are most commonly observed with liver cancer incidence as well as with increased or decreased rates of mortality.;Ideally, these association rules will be applied in future studies using liver cancer data extracted from other Electronic Health Record (EHR) systems. The main objective of making these rules available is to facilitate early detection guidelines for liver cancer and to evaluate current treatment options.