Nutrition and bone density in children with cystic fibrosis.

摘要

The purpose of these studies was to further research on bone density in children with cystic fibrosis, particularly as it pertains to nutritional parameters and care. The first paper presented a comparison of a group of 50 children with cystic fibrosis to a group of 32 control children. There were no significant differences between the groups in any of the pertinent bone density measurements. Serum 25(OH) vitamin D was positively correlated with spine density z score in the cystic fibrosis group.; The second paper, incorporating all of the information obtained from the first paper, describes an intervention study with the implementation of a fortified milk to determine the effects of additional calcium and vitamin D on bone density in the cystic fibrosis group. A follow-up bone scan was done. The fortified milk did not significantly improve bone density, but the fortified milk group did have significantly higher lung function scores on follow-up.