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Heritability of occlusal traits in primary dentitions of Brazilian twins.

机译:巴西双胞胎原发牙列咬合性状的遗传性。

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摘要

The purpose of this study is to determine the heritability of occlusal traits in primary dentitions of Brazilian Twins using a twin study design. 16 pairs of monozygotic (MZ) identical twins casts and 19 pairs of dizygotic (DZ) fraternal twins casts were obtained from the University of Pittsburgh. Occlusal traits were measured directly off the casts using an electronic digital caliper calibrated to measure to the nearest 0.01 mm. The occlusal traits investigated include: overjet, overbite, left and right molar sagittal relationship, inter-canine arch breadth, inter-molar arch breadth, maxillary and mandibular arch length. Heritability was computed using a variance component model implemented in the SOLAR (AAVSO, Cambridge, MA, USA) computer analysis package. The heritability estimates were determined to be 84% for overjet, 90% for overbite, 38% to 42% for molar classification, 61% for maxillary inter-canine breadth, 91% for maxillary inter-primary second molar breadth, 95% for maxillary arch length, 82% for mandibular inter-canine breadth, 92% for mandibular inter-primary second molar breadth, and 35% for mandibular arch length. These results indicated a range from moderate to highly heritable genetic influences on phenotypic expression of occlusal traits in the primary dentition.
机译:这项研究的目的是使用双胞胎研究设计来确定巴西双胞胎原发牙列的咬合特征的遗传性。从匹兹堡大学获得了16对同卵双胞胎(MZ)同卵双胞胎和19对异卵双胞胎(DZ)异卵双胞胎。使用已校准为精确到0.01毫米的电子数字卡尺直接在铸型上测量咬合性状。研究的咬合特征包括:上颌过冲,咬合,左右臼齿矢状关系,犬齿间弓宽,臼齿间弓宽,上颌和下颌弓长度。使用在SOLAR(AAVSO,剑桥,马萨诸塞州,美国)计算机分析程序包中实现的方差分量模型计算遗传力。确定的遗传力估计值是:上射血为84%,咬合为90%,臼齿分类为38%至42%,上颌犬齿间宽度为61%,上颌原发性第二磨牙宽度为91%,上颌为95%牙弓长度,下颌犬齿间宽度的82%,下颌原发性第二磨牙宽度的92%,下颌牙弓长度的35%。这些结果表明,对原发牙列中牙合特性表型的表达有中等到高度遗传的影响。

著录项

  • 作者

    Chen, Robert Yen Po.;

  • 作者单位

    State University of New York at Buffalo.;

  • 授予单位 State University of New York at Buffalo.;
  • 学科 Health Sciences Dentistry.; Biology Genetics.
  • 学位 M.S.
  • 年度 2006
  • 页码 40 p.
  • 总页数 40
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 口腔科学;遗传学;
  • 关键词

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