Effect of pathological changes in computer generated action potentials in lower limb muscles of children with cerebral palsy

摘要

Lower limb muscles of children with cerebral palsy undergo progressive pathological changes. Type-I fiber abundance and Type-II fiber deficiency are found to be common in these muscles. Both fiber types also suffer from atrophy. This paper investigates the effects of simulated physiological changes that occur in muscles of subjects with cerebral palsy using computer generated muscle action potentials (CGAPs). The results showed decrease in peak to peak amplitude, area under the curve and mean frequency and increase in rise time of the CGAPs of the subjects with cerebral palsy from those of normal subjects.