Structural Analysis of Human Proximal Femur for the Prediction of Biomechanical Strength ’In Vitro’. The Locally Adapted Scaling Vector Method.

摘要

We introduce an image structure analysis technique suitable in cases where anisotropy plays an importantrole. The so-called Locally Adapted Scaling Vector Method (LSVM) comprises two steps. First, a procedureto estimate the local main orientation at every point of the image is applied. These orientations are thenincorporated in a structure characterization procedure. We apply this methodology to High Resolution MagneticResonance Images (HRMRI) of human proximal femoral specimens IN VITRO. We extract a 3D local texturemeasure to establish correlations with the biomechanical properties of bone specimens quantified via the bonemaximum compressive strength. The purpose is to compare our results with the prediction of bone strengthusing similar isotropic texture measures, bone mineral density, and standard 2D morphometric parameters.Our findings suggest that anisotropic texture measures are superior in cases where directional properties arerelevant.