Importance of Physicochemical Understanding of Pharmaceutical Excipients for the Optimal Formulation Design

机译：药物赋形剂理化理解对最佳制剂设计的重要性

获取原文

获取原文并翻译 | 示例

页面导航

摘要
著录项
相似文献
相关主题

摘要

In this presentation, the physicochemical properties of pharmaceutical excipients will be introduced using several analytical methods for the optimal design of the solid dosage forms. The compressibility and disintegration properties of fast-disintegration tablets were discussed in a molecular level. The granulation mechanisms and dissolution properties of sustained release tablets ware also discussed using new analytical technology.

机译：在本演示中，将使用几种分析方法介绍药物赋形剂的物理化学性质，以优化固体剂型的设计。在分子水平上讨论了快速崩解片剂的可压缩性和崩解性质。还使用新的分析技术讨论了缓释片剂的制粒机理和溶出特性。

著录项

来源
《The Second Asian symposium on pharmaceutical sciences and technology》|2011年|23-25|共3页
会议地点 Xian(CN)
作者
Katsuhide Terada;
展开▼
作者单位

Faculty of Pharmaceutical Sciences, Toho University, Japan;

展开▼
会议组织
原文格式 PDF
正文语种 eng
中图分类药剂学;
关键词
crystallinity; surface free energy; wetting; ATR; Raman imaging; MRI;

机译：结晶度表面自由能润湿ATR；拉曼成像核磁共振;;

相似文献

外文文献
中文文献
专利

1. Selecting optimal pharmaceutical excipient formulation from life cycle assessment perspectives: A case study on ibuprofen tablet formulations [J] . Wang Danping, Cheow Wean Sin, Amalina Nur, Journal of Cleaner Production . 2021,第Apra10期

机译：从生命周期评估视角中选择最佳药物赋形剂制剂：对布洛芬片剂配方的案例研究
2. Physicochemical compatibility studies of triclosan and flurbiprofen with excipients of pharmaceutical formulation using binary, ternary, and multi-combination approach [J] . Aminu Nafiu, Chan Siok-Yee, Mumuni Momoh A., Future Journal of Pharmaceutical Sciences . 2021,第1期

机译：用二元，三元和多组合方法对药物制剂赋形剂的特异性化学兼容性研究
3. Application of design space optimization strategy to the development of LC methods for simultaneous analysis of 18 antiretroviral medicines and 4 major excipients used in various pharmaceutical formulations [J] . Védaste Habyalimana, Jérémie Kindenge Mbinze, Achille Loconon Yemoa, Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis . 2017,第期

机译：设计空间优化策略在三种抗逆转录病毒药物同时分析的LC方法开发中的应用和各种药物制剂中使用的4种主要赋形剂
4. Importance of Physicochemical Understanding of Pharmaceutical Excipients for the Optimal Formulation Design [C] . Katsuhide Terada Asian symposium on pharmaceutical sciences and technology . 2011

机译：对最佳配方设计的药物化学理解的重要性
5. Understanding and Predicting Pharmaceutical Excipient Variability and Performance using Spectroscopic and Multivariate Analysis Approaches [D] . Wang, Ting 2014

机译：使用光谱和多元分析方法了解和预测药物赋形剂的变异性和性能
6. Physicochemical Characterization of Grewia ferruginea Hochst. ex A. Rich Mucilage for Potential Use as a Pharmaceutical Excipient [O] . Tsadkan Gebremeskel Haile, Gereziher Gebremedhin Sibhat, Fantahun Molla 2020

机译：Grewia Ferruginea Hochst的物理化学特征。 Ex A.富含粘液的潜在用途作为药物赋形剂
7. ABSTRACTudThe purpose of this research is to obtain an optimal formulations of Black mulberry leaves dried noodle product by using Design Expert Application with Design Mixture D-optimal method.udThis research was done with two phases. The preliminary procedures research is to determine levels of antioxidant activity, chlorophyll content, and the levels of tannin that was contained in black mulberry leaves, the black mulberry leaf flour, a pare fruits, and pare flour. Primary research is to determine the best formulation by using a Mixture Design Expert Design D-optimal method, for a purpose is to optimized the Black mulberry leaf dry noodle. Responses in this studies are a chemical analysis response by using a crude fiber analysis and protein analysis. Physical response is water absorption. Sensory response are color, flavor, and odor.udBlack mulberry leaves dried noodles was made from wheat flour, black mulberry leaf flour, and pare flour, other materials such as an eggs, water, salt, and sodium bicarbonate, of the 16 formulations that has offered to produce an optimal formulation based on desirability which contains 39.69 Flour,14.25 Black Mulberry Leaves flour, 3.06 Pare fruit and flour amounted, and other materials are 30 water, 10 eggs, 2 salt, and 1 sodium bicarbonate. The formulation has been result by program 11,05 crude fiber content, 12.93 protein, 274.31 water absorption, 4,31 for color attribute, 3,87 for taste attribute, and 3,71 for aroma attribute.ududKeyword: Black mulberry leaf dried noodles, optimization. [O] . Leti Nurlatifah Alumni, Yudi Garnida DS, Tantan Widiantara DS 2017

机译：抽象 ud本研究的目的是通过使用带有Design Mixture D-最优方法的Design Expert Application获得黑桑叶干面条产品的最佳配方。 ud这项研究分两个阶段进行。初步程序研究是确定抗氧化剂活性，叶绿素含量以及黑桑叶，黑桑叶粉，果皮和果皮中所含单宁的含量。首要研究是通过使用Mixture Design Expert Design D-optimal方法确定最佳配方，目的是优化黑桑叶干面条。本研究中的反应是通过使用粗纤维分析和蛋白质分析进行的化学分析反应。物理反应是吸水。感官反应是颜色，味道和气味。黑桑叶干面条由小麦粉，黑桑叶粉和削皮粉，鸡蛋，水，盐和碳酸氢钠等其他材料制成，这16种配方可根据需要提供最佳配方其中包含39.69％的面粉，14.25％的黑桑叶面粉，3.06％的去皮水果和面粉，其他材料是30％的水，10％的鸡蛋，2％的盐和1％的碳酸氢钠。该配方是通过程序11,05％的粗纤维含量，12.93％的蛋白质，274.31％的吸水率，4.31的颜色属性，3,87的味道属性和3,71的芳香属性得出的。 ud关键字：黑桑叶干面条，优化。

Importance of Physicochemical Understanding of Pharmaceutical Excipients for the Optimal Formulation Design

摘要

著录项

相似文献

相关主题

期刊订阅