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PARAFFIN ACTUATED MICROMIRROR FOR ENDOSCOPIC OCT

机译:用于内镜OCT的石蜡激活微镜

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摘要

Microelectromechanical systems (MEMS) have great potential for use in gastrointestinal (GI) imaging. Ultrasound and magnetic resonant imaging can provide useful information about the GI tract, but only optical coherence tomography (OCT) delivered endoscopically can be used to perform an optical biopsy of the GI tissue. In monitoring a condition such as Barrett's esophagus, which typically requires regular random biopsies, the ability to achieve an optical biopsy is indispensible. While the existing method for obtaining an optical biopsy of the GI tract tissue produces functional images, there are drawbacks that could be improved upon. The gear-and-shaft assembly used to couple force from the motor at the proximal end to the distal imaging end requires a complex design [1]. By introducing a rotational MEMS device into the distal imaging end, a rotating optical coupling joint is no longer required at the proximal end, there is no need to precisely align the fixed fiber with the rotational drive shaft, and the metallic reinforcement sleeve can be eliminated leaving a simpler, more flexible delivery method [2]. In order to produce 3D OCT images, displacement in the z-direction needs to be coupled with rotation. A MEMS device that can achieve both vertical displacement and rotation further increases the simplicity of the device and decreases potential alignment and coupling errors. Our MEMS devices needs to be able to bend an OCT beam of light 90°, rotate that beam of light 360°, and simultaneously scan in the z-direction in order to produce 3D OCT images. Also, the device must fit inside the 1 mm diameter available in the endoscope. To accomplish this, we have designed, and are continuing to develop, a paraffin actuated micro mirror.rnThe thermal expansion properties of paraffin wax have often been utilized in MEMS devices [3, 4]. We have made use of these properties in designing a piston like actuator. Heat is applied to a reservoir of paraffin enclosed by a parylene membrane. The paraffin expands and pushes the post above it upward with the developed force from its expansion. The amount of paraffin in each reservoir is controlled by the reservoir's geometry and so by controlling the amount of heatrnapplied, we can control how far the post above it moves in the vertical direction. Each device has three heaters, three reservoirs, and three posts. All three posts are attached to a single mirror. By appropriately cycling the applied heat to each reservoir, we expect to be able to move the mirror in a spiral like fashion. This will bend an applied beam of light 90° and rotate it 360° while achieving displacement in the z-direction.
机译:微机电系统(MEMS)在胃肠道(GI)成像中具有巨大的潜力。超声和磁共振成像可以提供有关胃肠道的有用信息,但是只有通过内窥镜传送的光学相干断层扫描(OCT)可以用于对胃肠道组织进行光学活检。在监测诸如Barrett食管的疾病(通常需要定期进行随机活检)时,实现光学活检的能力是必不可少的。尽管用于获得胃肠道组织的光学活检的现有方法产生功能图像,但是存在可以改善的缺点。用于将力从近端的马达耦合到成像远端的齿轮和轴组件需要复杂的设计[1]。通过将旋转式MEMS器件引入远端成像端,不再需要在近端旋转光学耦合接头,无需将固定光纤与旋转驱动轴精确对准,并且可以省去金属增强套管留下了一种更简单,更灵活的交付方式[2]。为了产生3D OCT图像,z方向的位移需要与旋转耦合。既能实现垂直位移又能实现旋转的MEMS器件,进一步提高了器件的简单性,并减少了潜在的对准和耦合误差。我们的MEMS器件需要能够将OCT光束弯曲90°,将其旋转360°,并同时在z方向上扫描,以生成3D OCT图像。此外,设备必须安装在内窥镜可用的1毫米直径内。为此,我们已经设计并正在继续开发石蜡致动的微镜。石蜡的热膨胀特性经常被用于MEMS器件[3,4]。我们在设计类似致动器的活塞时利用了这些特性。将热量施加到被聚对二甲苯膜包围的石蜡容器中。石蜡膨胀并利用其膨胀产生的力向上推动其上方的柱。每个储层中的石蜡含量受储层几何形状的控制,因此,通过控制施加的热量,我们可以控制其上方的立柱沿垂直方向移动多远。每个设备都有三个加热器,三个储水箱和三个立柱。所有三个帖子都附加到单个镜像上。通过适当地循环施加到每个储罐的热量,我们期望能够以螺旋状移动镜子。这将使所施加的光束弯曲90°,并将其旋转360°,同时实现z方向的位移。

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