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Multi-wavelength adaptive optical fundus camera and continuous retinal imaging

机译:多波长自适应光学眼底照相机和连续视网膜成像

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摘要

We have constructed a new version of retinal imaging system with chromatic aberration concerned and the correlated optical design presented in this article is based on the adaptive optics fundus camera modality. In our system, three typical wavelengths of 550nm, 650nm and 480nm were selected. Longitude chromatic aberration (LCA) was traded off to a minimum using ZEMAX program. The whole setup was actually evaluated on human subjects and retinal imaging was performed at continuous frame rates up to 20 Hz. Raw videos at parafovea locations were collected, and cone mosaics as well as retinal vasculature were clearly observed in one single clip. In addition, comparisons under different illumination conditions were also made to confirm our design. Image contrast and the Strehl ratio were effectively increased after dynamic correction of high order aberrations. This system is expected to bring new applications in functional imaging of human retina.
机译:我们构建了涉及色差的视网膜成像系统的新版本,本文中提出的相关光学设计基于自适应光学眼底照相机模式。在我们的系统中,选择了550nm,650nm和480nm三种典型波长。经度色差(LCA)使用ZEMAX程序进行了折衷。整个设置实际上是在人类受试者上评估的,并且视网膜成像以高达20 Hz的连续帧速率执行。收集了位于中央凹旁位置的原始视频,并且在一个单一的夹子中清晰地观察到了圆锥形镶嵌以及视网膜脉管系统。此外,还进行了不同照明条件下的比较以确认我们的设计。动态校正高阶像差后,可以有效提高图像对比度和斯特列尔比。该系统有望在人类视网膜功能成像中带来新的应用。

著录项

  • 来源
    《Photonics and imaging in biology and medicine》|2009年|P.751910.1-751910.11|共11页
  • 会议地点 Wuhan(CN);Wuhan(CN)
  • 作者单位

    Key Lab on Adaptive Optics, Chinese Academy of Sciences, P.O. Box 350, Chengdu, Sichuan 610209, China Institute of Optics and Electronics, Chinese Academy of Sciences, P.O. Box 350, Chengdu, Sichuan 610209, China Graduate School, Chinese Academy of Sciences, Beijing 100864, China;

    rnKey Lab on Adaptive Optics, Chinese Academy of Sciences, P.O. Box 350, Chengdu, Sichuan 610209, China Institute of Optics and Electronics, Chinese Academy of Sciences, P.O. Box 350, Chengdu, Sichuan 610209, China;

    Key Lab on Adaptive Optics, Chinese Academy of Sciences, P.O. Box 350, Chengdu, Sichuan 610209, China Institute of Optics and Electronics, Chinese Academy of Sciences, P.O. Box 350, Chengdu, Sichuan 610209, China;

    Key Lab on Adaptive Optics, Chinese Academy of Sciences, P.O. Box 350, Chengdu, Sichuan 6;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 医用物理学;
  • 关键词

    adaptive optics; retina; chromatic aberration; continuous imaging;

    机译:自适应光学视网膜色差连续成像;

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