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Angioscopic observation of coronary lesions in Kawasaki disease

机译:川崎病冠状动脉病变的血管镜观察

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Abstract: Kawasaki disease is an acute systematic angiitis, specifically affecting the coronary arteries in young children. Coronary aneurysms develop in 10 to 15% of patients with Kawasaki disease. The coronary aneurysm frequently changes into coronary stenosis and obstruction. Hitherto, we could observe and access the severity of these coronary lesions with the use of two dimensional echocardiography and selective coronary angiography. Angiography is the most sensitive means available for diagnosing significant coronary lesions and their severity. However, it is insensitive for detecting intraluminal minute and pathologic changes such as intimal thickening, regeneration of endothelium and thrombus. Recent advance in fiberscopie technology, enabled us to observe the inside of coronary artery percutaneously. We tried to use this angioscopic technique for the observation of coronary lesions in eight patients with Kawasaki disease at chronic stage.!0
机译:摘要:川崎病是一种急性系统性血管炎,特别影响幼儿的冠状动脉。川崎病患者中有10%至15%会发生冠状动脉瘤。冠状动脉瘤经常变为冠状动脉狭窄和阻塞。迄今为止,我们可以通过二维超声心动图和选择性冠状动脉造影来观察和获取这些冠状动脉病变的严重程度。血管造影术是诊断重要冠状动脉病变及其严重程度的最灵敏手段。但是,它对于检测腔内分钟和病理变化(如内膜增厚,内皮和血栓的再生)不敏感。纤维复制技术的最新进展使我们能够经皮观察冠状动脉内部。我们试图使用这种血管镜技术来观察8例川崎病慢性期患者的冠状动脉病变。0

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