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Critical Review: Human Health Literature Related to Unconventional Oil and Natural Gas Development

机译:批评点评:与非传统石油和天然气开发有关的人类健康文献

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Background Development of oil and natural gas from unconventional resources (UOGD) has expanded rapidly in the last decade, and increased public and academic interest has led to a growing body of literature about its potential health effects. This review summarizes the epidemiological evidence and what the body of literature does and does not tell us about the relationship between UOGD and health. Methods The Health Effects Institute's Energy Research Committee (the Committee), consisting of multidisciplinary experts from across the U.S., along with HEI staff systematically reviewed the peer-reviewed and gray epidemiologic literature published between January 2000 and March 2018 by searching several electronic databases and consulting with expert stakeholders. The Committee elected to review analytical epidemiological studies worldwide with a primary focus on UOGD exposure and human health outcomes to assess whether the health of people living in locations affected by UOGD are adversely affected by the operations. Each study was assessed in duplicate for quality and risk of bias using an approach based on guidance from the National Toxicology Program Office of Health Assessment and Translation. Results The epidemiologic studies report associations between UOGD and various outcomes, including perinatal effects, asthma, cancer, hospitalizations and self-report health symptoms. Study authors discuss limitations of their studies, including reliance on imprecise proxies for UOG Exposure, with many noting that causality cannot be assessed without better exposure measures. This presentation will provide the Committee's findings about the strengths and weaknesses of this body of literature. Conclusions This systematic, impartial literature review will be useful to regulators, scientists, and others interested in understanding what is known about potential health effects of UOGD, what knowledge gaps remain, and how important knowledge gaps could be filled with future research.
机译:背景技术在过去十年中,来自非传统资源(UOGD)的石油和天然气(UOGD)的发展已经扩大,并且增加了公众和学术兴趣的增加导致了对其潜在健康影响的文学体弱。本综述总结了流行病学证据以及文学的身体所做的事,并没有告诉我们uogd和健康之间的关系。方法方法,由美国对美国的多学科专家组成的健康效果研究所(委员会)通过搜索多个电子数据库和咨询,系统地审查了2000年1月至2018年3月至2018年1月至2018年3月之间发布的同行和灰色流行病学文献与专家利益相关者。委员会选举审查全世界的分析流行病学研究,主要关注UOGD暴露和人类健康结果,以评估生活在受UOGD影响的地方的人们是否受到业务的不利影响。通过基于国家毒理学计划办公室的健康评估和翻译办公室的指导,每项研究重复评估偏差的质量和风险。结果流行病学研究报告了UOGD和各种结果之间的关联,包括围产期效应,哮喘,癌症,住院和自我报告健康症状。研究提交人讨论了他们的研究的局限性,包括依赖于UOG曝光的不精确代理,许多注意到不能在没有更好的曝光措施的情况下评估因果关系。本演示文稿将提供委员会关于该体内的优势和劣势的调查结果。结论这一系统,公正的文献综述将对监管机构,科学家和其他有兴趣了解uogd的潜在健康影响的人有用,仍然存在的知识差距,以及未来的研究如何填补知识差距。

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