Theoretical analysis of crosstalk in near-infrared topography

摘要

Crosstalk between changes in concentration of oxy- and deoxy-haemoglobin calculated by modified Lambert-Beer law in near-infrared topography is theoretically investigated. The change in intensity detected with source-detector pairs on the scalp caused by global or focal absorption change in the brain is predicted by Monte Carlo simulation. The topographic images of changes in oxy- and deoxy-haemoglobin are obtained from the changes in intensity detected with sourcc-dctcctor pairs on the scalp. The crosstalk depends on the relative position of the focal absorption change to source-detector pairs. The crosstalk is minimised when the focal absorption change is located below a measurement point that is the midpoint between a source and a detector.