Integrated control system based on MCU for the temperature and sampling of helical microfluidic PCR detection system

摘要

In this paper, based on the study of microbiological hazards real-time automatic alarm system for space applications and the "function integrated and structure miniature" of the microfluidic real-time PCR detection system, we have developed an integrated control system based on the MCU micro-processing chip for the control of constant temperature and sampling flow velocity of microfluidic PCR system. We have used the flexible polyimide film instead of traditional elements such as copper to facilitate the flow structure, which is characterized by small size, light weight and excellent heat transfer efficiency, applicable to the space environment. For the PID parameter tuning, by simulating the Z-N method of engineering turning based on the MATLAB/Simulink, a simple and efficient method for PID parameters turning is proposed in this paper. The practical application shows that the system is simple, strong applicability, high control accuracy, process visualization, fully automation control and adapt to the requirements of the space environment. It satisfies the development requirement of making the structural miniature and the function integrated. It can achieve the requirements of space applications by correcting and calculating the detection system in the conditions of weightlessness.