Analysis of the Curative Effect of the Treatment of the Three-dimensional Conformal Radiotherapy Combination with the Induction Chemotherapy in the Middle-late Nasopharyngeal Carcinoma

摘要

Objective: To observe and explore the clinical curative effect of the three dimensional conformal radiotherapy combination with the induction chemotherapy to treat the middle-late nasopharyngeal carcinoma patients. Methods: We select from February 2012 to February 2014 the clinical data of 98 middle-late nasopharyngeal carcinoma patients. They were retrospectively analyzed, and were divided into observation group and control group according to the treatment, each group are 49 cases, the observation group are received three dimensional conformal radiotherapy combination with the induction chemotherapy, the control group are accepted the three-dimensional conformal radiotherapy. Three dimensional conformal radiation therapies, chemotherapy is to TPF scheme, to observe the indexes including nasopharyngeal tumour and neck swelling lymph nodes complete remission rates, 1 year and 3 years of progression-free survival (PFS) and overall survival (OS), the incidence of adverse reactions. Results: Two groups of nasopharyngeal tumours and neck swelling lymph nodes complete remission rate, there was statistically significant difference comparison (P<0.05), the observation group of patients 1 year and 3 years of PFS and OS is significantly higher than the control group, significant differences are statistically significant (P<0.05). Conclusion: Three dimensional conformal radiotherapy combination with the induction chemotherapy can improve the PFS and OS of the middle-late stage nasopharyngeal carcinoma patients, although the incidence of adverse reactions, it does not affect the completion of treatment, and it is worthy of clinical popularization and application.