Effect of Tricalcium Phosphate-based Paste- and Foam-like Bone Grafting Materials on Bone Regeneration and Osteogenic Marker Expression in vivo

摘要

Both, TCP-P and TCP-F facilitated excellent bone regeneration of critical-size defects in the sheep scapula similar to that of the clinically established TCP granules while exhibiting a greater biodegradability. Hence, both TCP-P and TCP-F proved to be excellent bone grafting materials with slightly superior osteogenic capacities compared to the TCP-G, thereby providing TCP-based bone substitutes with advanced surgical handling properties for applications, in which granules are not a suitable form of application for grafting and reconstruction of a given bony defect.