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A Multiple Magnetoelastic Sensor System for Detection of Salmonella Typhimurium Using Pulse Method

机译:一种多磁形弹性传感器系统,用于使用脉冲法检测沙门氏菌伤寒沙门氏菌

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Magnetoelastic sensors show a resonance frequency decrease once target pathogens are attached to the sensors and thus add a small mass to the sensors. These sensors are fast, sensitive, and have higher mass sensitivity with smaller sized sensors. However, signals from smaller sensors are weaker and have more noise due to manufacturing defects. In this paper, we present a pulse biosensor system that is able to avoid bias magnetic field and allows simultaneous detection using multiple sensors. With multi-sensors, the effect of a manufacturing defect is decreased and we get the benefit of averaging for more accurate and reliable results. Stability tests show that the variance of frequency detection is less than 122 ppm of its resonance frequency. Real detection of pathogen is demonstrated using Salmonella typhimurium and the results show that multiple magnetoelastic biosensors are able to detect S. typhimurium simultaneously and offer good sensitivity and reliability.
机译:一旦靶病原体连接到传感器,磁力弹性传感器显示共振频率降低,从而向传感器增加一个小质量。这些传感器快速,敏感,具有更高的质量敏感性,具有较小的尺寸传感器。然而,来自较小传感器的信号较弱并且由于制造缺陷而具有更多的噪音。在本文中,我们介绍了一种能够避免偏置磁场的脉冲生物传感器系统,并允许使用多个传感器同时检测。利用多传感器,制造缺陷的效果降低,我们得到了更准确和可靠的结果的平均效益。稳定性测试表明,频率检测的方差小于其共振频率的122ppm。使用Salmonella Typhimurium对病原体进行实际检测,结果表明,多种磁力弹性生物传感器能够同时检测S. Typhimurium并提供良好的敏感性和可靠性。

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