Effects of IR laser radiation in thyroid follicular cells: fine structural and stereological study

摘要

We have examined the results obtained from the stereological ultraestructural study of follicular cells in thyroid glands treated with IR laser (904 nm). We studied 40 wistar rats exposed to radiation with doses of 46,80 J/cm2. They were sacrificed 1 and 180 days after the treatment. A stereological study of the volume and surface density was made in mitochondria, rER. Gogi complex and cytoplasmic granules. In the rats sacrificed 1 day after exposure to laser radiation, the thyrocited showed minimal morphological changes. In the rats sacrificed after a long period (180 days) the thyrocites showed a significant increase of volume and surface densities of rER, that may mean decreased capacity of the cells to synthesize thyroglobulin. Volume and surface densities of the citoplasmic granules experienced a significant increase.