Evaluation of primary human endothelial cells cultured on newly developed 3D-printabIe polymer surfaces

摘要

Medical implants need to fulfill a variety of requirements regarding long term duration, design, function and biocompatibility [1]. To obtain these versatile standards in one application the demands to the materials are high [2]. In our work, polymer materials were designed for the buildup of an artificial 3-dimensional (3D) blood vessel system using a 3D-inkjet printing process. A biocompatible photo-curable ink that fits the parameters of the inkjet process (e.g. viscosity, surface tension etc.) has been generated. Furthermore, the wanted properties of the cured 3D scaffolds like flexibility were setup. The new polymers, surfaces are being developed, produced and in cell cultivation experiments systematically analyzed for their applicability with endothelial cells.