Interplay of matrices in cartilage synovial fluid combine undermoderate and high loadings

摘要

The interplay of the constituents of articular cartilage synovialfluid is examined from the biochemical and rheological study on bovinejoint. Results show an inverse relationship between the changes in thehyaluronic acid and proteoglycan contents of synovial fluid andarticular cartilage with corresponding alterations in the rheologicalproperties of synovial fluid. The study indicates that inter-movement offluid solutes across the cartilage and synovial fluid plays an importantrole in the pathophysiology of osteoarthritis