Clinical studies of the combined action of ultraviolet and laser (662 nm) radiation with methylene blue for local therapy of defects of oral mucosa in chronic recurrent aphthous stomatitis

摘要

The work is devoted to the determination of the antibacterial activity of methylene blue under the action ofultraviolet radiation, laser radiation (660 nm), as well as their combined effect on standard strains of the bacteriaCandida albicans, Staphylococcus aureus FDA 209P and Lactobacillus in vitro. When exposed to all the testedstrains, a tendency was revealed with the most pronounced inhibitory effect with the combined action of laser andultraviolet radiation together with the MB solution. Clinical studies of the in vivo use of methylene blue with thecombined effect of ultraviolet and laser radiation (660 nm) in the treatment of chronic recurrent aphthousstomatitis in humans have also been conducted.