Mueller matrix polarimetric imaging (MMPI) provides precise microstructural information of biological samplesand has been applied to the detections of various abnormal tissues. Once the Mueller matrix is determinedfor a particular anisotropic material, polar decomposition is applied to determine the singular values of opticalanisotropies, such as depolarization, diattenuation, retardance and optical rotation. In this work, ex-vivo can-cerous and noncancerous tissues were imaged by the MMPI technique using 3 different radiation wavelengths(460, 532 and 633 nm). The samples under study were cancerous and noncancerous tissues from colon. Theresults show that the optical anisotropies from biological samples are different. As we know, cancer changes thestructure and concentration of biomedical substances from healthy tissue. One of the structures that is affectedby cancer is collagen. This structure contributes to the diatenuation and retardance values. Therefore the valuesof diatenuation and retardance are different from the malignant and healthy tissues. We demonstrate that MMPIand polar decomposition are useful tools to discriminate healthy tissue and cancerous tissue from different partsof the body.
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