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A scalable discrete event stochastic agent-based model of infectious disease propagation

机译:基于可扩展离散事件随机代理的传染病传播模型

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We propose a newstochastic model of infectious disease propagation. This model tracks individual outcomes, but does so without needing to create connectivity graphs for all members of the population. This makes the model scalable to much larger populations than traditional agent-based models have been able to cope with, while preserving the impact of variability during the critical early stages of an outbreak. This contrasts favorably with aggregate deterministic models, which ignore variability, and negates the requirement to assume ???convenient??? but potentially unrealistic distribution choices which aggregate stochastic models need in order to be analytically tractable. Initial explorations with our new model show behaviors similar to the observed course of Ebola outbreaks over the past 30+ years???while many outbreaks will fizzle out relatively quickly, some appear to reach a critical mass threshold and can turn into widespread epidemics.
机译:我们提出了一种传染病传播的新随机模型。该模型可跟踪单个结果,但无需创建所有人群的连接图。与传统的基于代理的模型相比,这使得该模型可扩展到更大的人群,同时保留了爆发关键早期阶段的可变性影响。这与总的确定性模型形成了鲜明的对比,后者忽略了可变性,并否定了假设“方便”的要求。但是汇总随机模型可能需要不切实际的分布选择,才能使其在分析上易于处理。使用我们的新模型进行的初步探索表明,其行为与过去30多年来观察到的埃博拉疫情相似。虽然许多疫情会相对迅速地消失,但有些疫情似乎已达到临界质量门槛,并可能演变成广泛的流行病。

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    《Winter Simulation Conference》|2015年|151-158|共8页
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