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FLOW INCREASES ENDOTHELIAL MIGRATION AND INHIBITS SMOOTH MUSCLE CELL PROLIFERATION IN ARTERY AND CO-CULTURE MODELS

机译:流动增加内皮迁移,抑制动脉和共同培养模型中平滑的肌细胞增殖

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Arterial restenosis associated with intimal hyperplasia at stent revascularization sites remains the major cause of long-term failure. The objective of this study was to determine the effect of flow in promoting endothelial cell migration and the effect of re-endothelialization on smooth muscle cell (SMC) proliferation. This study demonstrated that re-endothelialization reduces SMC proliferation and migration and provides model systems to study approaches to increasing endothelial healing.
机译:与支架血运重建站点的内膜增生相关的动脉再狭窄仍然是长期失败的主要原因。本研究的目的是确定流动对促进内皮细胞迁移的影响及重新内皮化对平滑肌细胞(SMC)增殖的影响。该研究表明,重新内皮化可降低SMC增殖和迁移,并提供模型系统,以研究增加内皮愈合的方法。

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