Evaluation of intra-aneurismal hemodynamics after stent placement in a pulsatile side wall model using laser Doppler anemometry

摘要

Treatment of intracranial aneurysms by means of hemodynamic modification with the use of novel stent designs is burgeoning area of research. Despite promising results with recently approved implants there is no reliable method to predict long term success of this technique yet. We used Laser Doppler anemometry (LDA) to evaluate the influence of different stent designs on intra-aneurismal flow in a pulsatile aneurysm model. The effective reduction of flow was shown to be negligible with standard self expanding stents and depended on both the stent design and appropriate positioning of dedicated flow diverters. Our results show that Laser Doppler anemometry is a feasible method to quantify intra-aneurismal flow and flow reduction efficacy of stents in vitro.