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Random Networks in a Distributed Computing Environment: An Approach to the Transmission Dynamics of Epidemic Diseases

机译:分布式计算环境中的随机网络:一种流行病传播动力学的方法

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Random networks are emerging in epidemiology as a way of simulation more realistic random contact behaviours. A network is a set of nodes representing individuals. Labels or properties may be assigned to each node, for instance, age, sex, state respect to disease (susceptibility, infection, recovery, etc.). Nodes are connected by ties that represent disease transmission paths. Once the network model and the disease evolution rules are stated, it is possible to simulate the evolution of the network over time and study the effect of disease on the population.Moreover, random networks provide an easy way of modelling those scenarios where it is required the monitoring of the specific individuals, the design of single or combined vaccination strategies or to control and apply therapies in chosen target groups, something difficult to achieve in continuous models. However, essential aspects in epidemiology like the model fitting with data in order to obtain the transmission rate of a disease in a specific region turns out to be highly complex in computational terms (requiring for an average desktop computer several weeks, months or even years of calculation time) whereas it is an issue with some valid approaches in continuous models which are able to solve the model in an affordable quantity of time.In this paper, we present the description of a computational system following the paradigm of distributed computing, which will allow the estimation of parameters in random network epidemic models. This paradigm consists of a server that delivers tasks to be carried out by client computers. When the task is finished, the client sends the obtained results to the server to be stored until all tasks are finished and then, ready to be analysed.
机译:流行病学中出现了随机网络,作为一种模拟更现实的随机接触行为的方式。网络是代表个人的一组节点。可以将标签或属性分配给每个节点,例如年龄,性别,疾病状态(易感性,感染,恢复等)。节点通过代表疾病传播路径的纽带连接。一旦确定了网络模型和疾病演变规则,就有可能模拟网络随时间的演变并研究疾病对种群的影响。 此外,随机网络提供了一种简便的方法,可以对那些需要监控特定个体,设计单一或联合疫苗接种策略或控制并在选定的目标人群中应用疗法的情况进行建模,而这在连续模型中很难实现。但是,流行病学的基本方面,例如为了获得特定区域内疾病的传播率而对数据进行拟合的模型,在计算方面变得非常复杂(平均台式计算机需要数周,数月甚至数年的时间,计算时间),而连续模型中的某些有效方法却能够在可承受的时间内解决该问题,这是一个问题。 在本文中,我们按照分布式计算范式介绍计算系统,这将允许估计随机网络流行模型中的参数。该范式由一台服务器组成,该服务器交付要由客户端计算机执行的任务。任务完成后,客户端将获取的结果发送到服务器进行存储,直到所有任务完成,然后准备进行分析。

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