Oxygen saturation in arterial and venous occlusions for an animal flap model

摘要

We studied ischemia and reperfusion in island groin flaps for nine Charles River rats. When the artery and/or vein are clamped, the oxygen saturation of hemoglobin (StO2) measured by an infra-red spectroscopic device (ViOptix, Inc., Fremont, CA) dropped significantly. The drop in arterial occlusion was usually faster than that in venous occlusion. When the clamp was released after more than 1 hour of vessel occlusion, the StO2 value came back, typically not to the pre-occlusive level but only about half of it.