Properties and release profiles of poe-peg-poe triblock copolymer microspheres

摘要

Poly(ortho ester) (POE) has been used as a carrier for delivery of various drugs (1-2). It is an attractive material for implant device such as disc, rod and tablet due to its promising surface erosion mechanism for drug release. By designing proper compositions of POE, constant drug release rate can be achieved.