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Stimulation efficacy of chamber-type, thin-film microelectrode

机译:腔室型薄膜微电极的刺激功效

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摘要

A computational model of a chamber-type, thin-film stimulating microelectrode was developed to study the distribution of the current density within the chamber. The three-dimensional model was based on Laplace's equation. The model, in conjunction with published experimental observations, provided information on the stimulation efficacy of the chambered electrode within neural tissue. In comparison to the performance of unchambered electrodes with the same effective stimulating area, the chambered electrode can potentially inject more current and stimulate more neural tissue. In comparison to unchambered electrodes with the same physical size, the chambered electrode can operate more selectively for nearby neural tissue. Thus, the chamber design has a greater dynamic range of operation.
机译:建立了腔室型薄膜刺激微电极的计算模型,以研究腔室内电流密度的分布。三维模型基于拉普拉斯方程。该模型与已发表的实验观察结果相结合,提供了有关神经组织内带腔电极的刺激功效的信息。与具有相同有效刺激区域的无室电极的性能相比,有室电极可以潜在地注入更多的电流并刺激更多的神经组织。与具有相同物理尺寸的非腔室电极相比,带腔室的电极可以针对附近的神经组织更有选择性地操作。因此,腔室设计具有较大的动态工作范围。

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