Virtual Reality Training with Passive Haptic Feedback for CryoEM Sample Preparation

摘要

We present an immersive virtual reality training system cryoVR with passive haptic feedback for training biological scientists preparing bio-sample for Cryo-Electron Microscopy (CryoEM). CryoEM requires the user to conduct careful operations on expensive delicate equipment. To minimize the risk and interruption of crucial research work, we tried to mimic the real lab using VR to let trainer practice in a virtual environment. We used 3D printed objects to provide passive haptic feedback in order to achieve a more realistic training experience. Participants are able to interact with the equipment in the virtual environment by moving or touching physical models. We developed all the necessary operations with haptic feedback, including moving, clicking, pouring, rotating, polling and pushing. By following instructions provided by our virtual reality simulator and interacting with physical objects, trainees will learn how to operate CryoEM with low cost and risk. By developing our training system, we explore the benefits, limitations and precautions of embedding haptic feedback to scientific VR training.