Spectral Photon-Counting CT imaging of Cold Labelled Monoclonal Antibody Drug Delivery to Raji and HER2 Positive Beast Cancer Cells - A Phantom Study

摘要

The current study successfully established methodology that aimed to quantify the delivery of drugs to a specific site of interest. The results showed the ability of SPCCT imaging to provide additional information in energy images. Analyzing the spectral response alone could not identify what materials were present due to a lack of k-edge. However, material decomposition (MD) identified both the material and quantified the amount of drug present