Re-vascularization of Pancreatic Islets with Self-assembled Endothelial Network

摘要

A novel approach was developed to assemble EC network. The EC network enhanced vascularization in subcutaneous space which is well-known as an attractive but challenge site for pancreatic islet transplantation. Rat islets pre-vascularized with EC network achieved re-vascularization in vivo, and realized hyperglycemia prevention in diabetic mice.