Bacteriostatic Characteristics of Silicon Nitride, Polyetheretherketone, and Titanium Biomaterials

摘要

Conclusions: Si_3N_4, PEEK, and titanium surfaces demonstrated significant differences in bacterial adhesion and proliferation for both gram-positive S epidermidis and gram-negative E coli, particularly at 48 hours post-inoculation. Implant-related infections are a serious clinical concern, requiring major surgery and prolonged antibiotics, with attendant morbidity and increased healthcare costs. Identifying biomaterial surfaces that inherently resist biofilm adhesion and bacterial expression is an important strategy addressing implant-related infections. Si_3N_4 appears to provide favorable bacteriostatic characteristics in comparison to PEEK and Ti6Al4V.