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Long-term follow-up case study of atrial fibrillation after treatment

机译:治疗后房颤的长期随访病例研究

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摘要

A case study is presented, based on long-term ECG measurements of a patient with diagnosed persistent atrial fibrillation (PeAF) that undergone the classical diagnostic procedures. The long-term measurements have been performed with an ECG body sensor. Based on the European Heart Rhythm Association (EHRA) guidelines for treatment of atrial fibrillation the left atrial catheter cryo-ablation with an endpoint of pulmonary vein isolation was performed. After the cryo-ablation PeAF still persists, therefore an additional catheter radiofrequency ablation was performed. After the second procedure and in combination with antiarrhythmic drugs the atrial fibrillation (AF) was controlled on the level of relatively rare and short documented AF episodes. A detailed analysis of a long-term measurement has enabled detection of a large spectrum of arrhythmias, which have been documented over a ten-week period of measurements. Those include atrial extrabeats and nonsustained atrial tachycardias that might be the initial triggers for AF. The initial study motivates new hypotheses about the long-term impact of ablation procedures and antiarrhythmic drugs on the outcome of medical therapies, which deserves to be further elucidated with a larger and more systematic study.
机译:基于对经过经典诊断程序诊断为持续性房颤(PeAF)的患者的长期ECG测量,提出了一个案例研究。长期测量已使用ECG人体传感器进行。根据欧洲心律协会(EHRA)的房颤治疗指南,进行了左房导管冷冻消融并以肺静脉隔离为终点。冷冻消融后PeAF仍然持续存在,因此进行了额外的导管射频消融。在第二次手术后,并结合抗心律失常药物,将房颤(AF)的水平控制在相对罕见和文献记载较短的AF发作水平上。长期测量的详细分析使得能够检测到大范围的心律不齐,这些心律失常已在十周的测量期内得到了记录。这些包括房性心跳过快和不持续的房性心动过速,这可能是房颤的最初诱因。最初的研究激发了有关消融手术和抗心律失常药物对药物治疗效果的长期影响的新假说,值得通过更大范围,更系统的研究进一步阐明。

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